As PhD student, I am working on the implementation of lung cancer screening in high-risk (former) smokers in the first line zone ZORA (ZORALCS study). Lung cancer remains the leading cause of cancer mortality, worldwide and in Belgium. Prevention and early detection are considered the cornerstones to increase the likelihood of successful treatment. There is strong scientific evidence that lung cancer screening by annual low-dose CT scan in a high-risk population of (former) smokers significantly reduces mortality.