November 2019 - Antwerp, Belgium
Meeting objectives:
- Provide an overview of the current situation of the HPV vaccine for adults.
- Discuss the immunogenicity, safety and efficacy data of existing HPV vaccine studies in adults.
- Gain insight into the efficacy of the HPV vaccine at the mucosal level and systemic level.
- Discuss ways and methods to conduct research on the potential benefits of vaccinating exposed adults.
- Discuss the challenges and benefits of vaccination of adults including high risk groups.
- Discuss cervical cancer elimination strategies.
- Discuss the potential implications of vaccination of adults on vaccine supplies in Low and Middle-Income Countries (LMIC).
November 14, 2019
OPENING AND OBJECTIVES
- Introduction. (Pdf, 1.600 kB)
Alex Vorsters
SESSION 1: SITUATIONAL ANALYSIS OF HPV VACCINATION OF ADULTS: IMUNOGENECITY AND SAFETY DATA
Chairs: Alex Vorsters & Pierre Van Damme
- Efficacy and safety of prophylactic HPV vaccination in adults.
Marc Arbyn
- Immunogenicity and tolerability of HPV vaccine in women aged 15-55 years; study findings and way forward. (Pdf, 726 kB)
Tino F. Schwarz
- Questions & Discussion
SESSION 2: HPV IMMUNOLOGICAL DYNAMICS AT MUCOSAL AND SYSTEMIC LEVEL
Chairs: Mario Poljak & Marc Arbyn
- Potential Benefits of HPV Vaccine in sexually active women: delivering the promise. (Pdf, 515 kB)
John Schiller
- Immune cross talk of HPV Specific Antibody Response; Cross Reactivity, Neutralizing Activity, Mucosal Secretion and Infection Prevention. (Pdf, 2.036 kB)
Fiona RM van der Klis
- Vaccine-induced HPV-specific antibodies in cervicovaginal secretions. (Pdf, 1.159 kB)
Jade Pattyn
- Immunising older cohorts : pros and cons (Pdf, 310 kB)
Margaret Stanley & Xavier Bosch
- Questions & Discussion
SESSION 3: COMPREHENSIVE ANALYSIS OF CHALLENGES AND POTENTIAL BENEFITS OF HPV VACCINATION OF ADULTS
Chairs: Eduardo Franco & Iacopo Bausanno
- Pap smear collection: an increased risk of HPV infection? An objective study in rhesus macaques’ model. (Pdf, 2.506 kB)
John Schiller
- HPV vaccine post treatment: a pathway to prevent disease relapse.
Marta del Pino
- HPV vaccination in relation to conization: A Danish nationwide study. (Pdf, 340 kB)
Susanne Krüger Kjær
- Questions & Discussion.
- Transmission Reduction and Prevention with HPV Vaccination (TRAP-HPV) study. (Pdf, 733 kB)
Aaron MacCosham and Eduardo Franco
- Predicting cohort-specific cervical cancer incidence from population-based HPV prevalence surveys.
Iacopo Bausanno
- Overview of Health Economics Models for HPV Vaccination of Mid-Adults. (Pdf, 682 kB)
Harrell Chesson
- Questions & Discussion.
- Breakout Session
Chairs: Paolo Bonanni & Susanne Krüger Kjær
- Pap smear; an increased risk for HPV infections? – How to deal with it?
- Are vaccinated women less prone to transmit infections – What are the ways to investigate it?
- Plenary feedback from different groups
November 15, 2019
SESSION 4: HPV VACCINATION OF HIGH-RISK GROUPS
Chairs: Mira Kojouharova & Sharon Hanley
- Directionality of HPV Infection transmission in heterosexual couples; a systematic review and meta-analysis (Pdf, 649 kB)
Aaron MacCosham
Eduardo Franco
- HPV Vaccination for sex workers: finding a balance between pros and cons. (Pdf, 461 kB)
Maarten Schim van der Loeff
- Baseline HPV Prevalence in rectal swabs from men attending a sexual health clinic in Scotland: assessing the potential impact of a selective HPV Vaccination programme for men who have sex with men. (Pdf, 320 kB)
Ross Cameron
- Questions & Discussion
SESSION 5: LIMITATIONS AND ELIMINATION GOALS
Chairs: Mark Kane & Luidmila Mosina
- Towards cervical cancer elimination: the context of HPV Vaccination. (Pdf, 2.826 kB)
Paul Bloem
- Questions & Discussion
BREAKOUT SESSIONS
Chairs: Paul Bloem & Emilie Karafillakis
- Outcome of the meeting, current challenges and strategies to deal with challenges: Where do we stand today?
- Plenary feedback from each group and discussion
CONCLUSION OF THE MEETING
Chairs: Pierre Van Damme & Xavier Bosch
- Conclusion (Pdf, 213.74 kB)
- Closing remarks