09/02/22 - Dustin (ESR #14)
In my PhD-project, I investigate the cardiotoxic effects of doxorubicin, a common chemotherapeutic drug. This drug is one of the most used and highly effective chemotherapeutics. I specifically look for the earliest signs of these cardiac adverse effects. Thus, patients at risk can be identified before they even develop severe cardiac injuries. If you want to find out how I do this check out my previous flyer!
My PhD project is conducted at the University of Antwerp, where we have the possibility to run in vivo, in vitro or ex vivo experiments. However, in my experience our research is limited to the expertise and infrastructure available in our labs. Within the INSPIRE project, I have the chance to increase my scientific outcome by combining expertise and facilities from both universities and companies.
In the beginning of 2022, I will spend a few weeks at UCB Pharma in Brussels to perform additional experiments at UCB’s state-of-the-art facilities. More specifically, together with my UCB colleague Martina Cherubin 'ESR #2), I will perform highly specific molecular analysis of possible biomarkers (microRNAs) in the blood and heart samples, previously collected at the University of Antwerp. Eventually, this will lead to a better understanding of the (molecular) damage this specific chemotherapeutic can cause.