'Frozen' aptamers
The on-site and highly selective detection of important target analytes such as antibiotic residues in wastewater is an open challenge. In this project, we aim to better understand and improve analytical detection systems that use aptamers for the selective recognition of molecules of interest followed by the generation of electrical signals (current, potential, resistance) upon binding. These electrochemical experiments are combined with ITC and NMR measurements (collaboration with Ghent University) to obtain a multi-analytical approach to study aptamer-target interactions. In this way, we hope to contribute to the development of more robust aptasensors.
