What we do
The Centre for the Evaluation of Vaccinations (CEV): a clinical trial centre, specialized in the conduct of vaccine trials:
⇒ Phase I until phase IV trials.
⇒ Trials for a range of companies.
⇒ In all age groups (from infants till elderly).
⇒ Pre-licensing vaccine trials.
⇒ Evaluating vaccine uptake and the operational aspects of vaccination.
⇒ Behavioural studies and basic vaccine research.
We conduct vaccine trials related to:
- vaccine safety
- reactogenicity
- immunogenicity and efficacy
- assessment of different dosages, schedules, formulations
- long-term follow-up
- mathematical modelling of the persistence of antibodies induced by different vaccines
Ongoing and completed studies since its official inauguration in 1994:
In adults
- hepatitis A vaccines
- hepatitis B vaccines
- combined hepatitis A and B vaccines
- combined vaccine against diphtheria, tetanus and pertussis
- flu vaccines (pandemic and seasonal)
- herpes simplex (HSV) vaccines
- human papilloma virus (HPV)
- S. Typhi
- Non-type able H.influenza
In children and adolescents
- hepatitis A vaccines
- hepatitis B vaccines
- combined hepatitis A and B vaccines
- combined vaccine against diphtheria, tetanus and pertussis
- flu vaccines
- Huiman papilloma virus (HPV)
In infants and toddlers
- candidate vaccine against polio
- RSV candidate vaccine
- candidate vaccines against pneumococcal disease
- rotavirus candidate vaccine
In specific risk groups
- hepatitis B vaccine in institutionalised mentally retarded
- flu vaccine in the elderly
- RSV vaccine in the elderly
Team members
Pierre Van Damme
Valerie Asselman
Ilse De Coster
Joanna Merckx
Leen Suykens
Hilde Revets
An Konings
Kanchamala Withanage
Serge Broodhaers
An (Annemie) Bruynseels
Anna (Annelies) Van Winckel
Els Verheyen