SPIN-D
The primary aim of this research was to examine the impacts of various anti-motion medications on the vestibular system and their effects on cognitive functions, with the ultimate goal of identifying a potential treatment for spacemotion sickness. To accomplish this objective, the study pursued several research goals: (i) Investigating the effects of baclofen, meclizine, dimenhydrinate combined with cinnarizine, promethazine combined with d-amphetamine, and intranasal scopolamine on the different vestibular end organs, i.e. thesemicircular canals, the utricles and saccules. (ii) To assess the influence of these medications on cognitive processes such as working memory, short-term memory, implicit memory, and psychomotor performance. (iii) Determining the side-effects profile of each of the tested medication. (iv) Identifying which medications demonstrate the most favorable balance between vestibular and cognitive effects for the alleviation of spacemotion sickness.
Duration: 2010 - 2014
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SPIN-D
