Medicinal Chemistry

Research focus

The medicinal chemistry research of UAMC is focused on the therapeutic domains of inflammation, cell death/survival and infectious diseases. We aim to develop chemical tool compounds that are used in the characterisation and validation of novel targets, and that will lead to novel hit and lead compounds in drug discovery programmes. In addition, we rely heavily on computational drug design methods such as free energy perturbation, QM/MM simulations and chem-informatics-based SAR.