Drug validation

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  • Vascular calcification inhibitors
  • Phosphate binders
  • Drug repurposing
  • Ferroptosis inhibitors

Mechanistic studies

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  • Mineral homeostasis
  • Kidney, vessel & bone interaction
  • Vascular stiffness
  • Cell death & ferroptosis
  • Senescence & regeneration
  • Transgenics

Experimental models

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  • Acute kidney injury (AKI)
  • Chronic kidney disease (CKD)
  • Kidney transplantation
  • Nephrocalcinosis
  • Vascular calcification
  • Bone loss (osteoporotic, CKD-induced)
  • Sepsis
  • Multi-organ failure

Diagnostics

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  • Kidney injury (urine/tissue)
  • Metal and trace element analysis
  • Bone morphometry
  • Critical illness (plasma/urine)
  • Cell death and inflammation biomarkers

Clinical studies

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  • Drug repurposing
  • Observational cohort studies