Epidemiological, preclinical and animal studies support phytomedicinal benefits of mangiferin (purified from mangotree Mangifera Indica), withaferin A (purified from Withania Somnifera) or thalassiolin (purified from Thalassia testudinum) in the prevention or treatment of  metabolic & cardiovascular diseases, cancers, infectious disease or neuronal disorders. By integrating epigenomic, transcriptomic, microRNomic, kinomic (chemo)proteomic approaches we want to identify key signalling pathways and molecular targets of phytochemicals responsible for antiviral effects, chemoprevention or  therapy sensitisation (ferroptosis) in various in vitro/in vivo disease models.

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