MobiliTraIN: Unlocking the Full Potential of Ion Mobility High-Resolution Mass Spectrometry
MobiliTraIN, an EU-funded Marie Skłodowska-Curie Actions Doctoral Network, successfully started in February 2024. Over four years, the project wants to harness the full potential of ion mobility-high resolution mass spectrometry (IM-HRMS), the next-generation analytical platform, in research and industry.
Why do we need IM-HRMS? This technology aids in characterising complex mixtures and identifying individual components with greater precision. As a result, IM-HRMS facilitates advancements in various fields such as biology, environmental science and material research.
What challenges is MobiliTraIN addressing? The lack of standardisation in data collection, analysis, and reporting across different IM-HRMS instrument types, laboratories and disciplines hinders meeting strict regulatory demands. MobiliTraIN aims to change this by creating standardised reference materials and protocols, elevating the reliability of IM-HRMS and making it the preferred choice for routine compound identification and characterisation.
From innovation to impact: Through the first doctoral training programme dedicated to IM-HRMS, MobiliTraIN fosters innovation and collaboration to overcome fragmentation in the uptake of the IM-HRMS technology. The standardised reference measurement procedures developed by MobiliTraIN will help ensure the quality and safety of medications, improve assurance of food and water safety, and contribute to the emergence of new applications of IM-HRMS across Europe’s key industries, e.g. in pharmaceuticals, biotechnology, clinical applications, industrial chemistry, environmental, as well as security and forensics.
A multidisciplinary consortium: MobiliTraIN brings together 9 Beneficiaries and 13 Associated Partners from 8 countries including IM-HRMS experts from industry and academia. This multidisciplinary consortium, coordinated by Assoc.Prof. Tim Causon from BOKU, the Vienna-based University of Natural Resources and Life Sciences, is well-equipped to drive IM-HRMS innovation and advance its adoption across sectors.
Follow MobiliTraIN‘s progress on our website and LinkedIn and check the interview given by Tim Causon with LCGC at Analytica 2024.
At the Toxicological Centre, we host DC8: IM-HRMS approaches for increasing confidence in the assessment of contaminants of emerging concern in indoor environment and humans. Our DC will 1) develop LC-DTIM-HRMS approaches for the broad screening of CECs present in the indoor environment and humans, 2) deliver new experimental methods for CCS database generation for compounds associated with hazardous environmental properties, and 3) increase the knowledge on CECs regarding their distribution in the indoor environment and humans.