Development of non-animal test strategies 

Can we use zebrafish embryos and even simpler assays as an alternative to the current fish toxicity tests for chemical safety evaluation based on our understanding of toxicological mechanisms?

Human toxicology 

Can a zebrafish disease model aid in understanding the role of environmental pollutants in the origin of human disease (e.g., obesity)? How does this affect reproductive capacity?

Ecotoxicology 

How do pollutants interact with normal cellular processes in fish embryos? How does this lead to adverse effects such as morphological abnormalities, altered swimming behaviour and reduced growth?