Design, synthesis and evaluation of novel activity-based probes and inhibitors for trypsin-like serine proteases : focus on Dry eye disease (DED) and Irritable bowel syndrome (IBS)
Source
Antwerp, University of Antwerp, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, Department of Pharmaceutical Sciences, 2023,xi, 289
The potential role of regulated cell death in dry eye diseases and ocular surface dysfunction
Source
International journal of molecular sciences - ISSN 1422-0067-24:1 (2023) p. 1-21
Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases
Source
Frontiers in Chemistry - ISSN 2296-2646-10 (2023) p. 1-17
Improved synthesis of the selected serine protease uPA inhibitor UAMC-00050, a lead compound for the treatment of dry eye disease
Source
Organic process research and development - ISSN 1083-6160-26:10 (2022) p. 2937-2946
Proteases and their potential role as biomarkers and drug targets in dry eye disease and ocular surface dysfunction
Source
International journal of molecular sciences - ISSN 1422-0067-23:17 (2022) p. 1-14