Study of the conformational dynamics of prolyl oligopeptidase by mass spectrometry : lessons learned

Source
Journal of medicinal chemistry - ISSN 0022-2623-67:12 (2024) p. 10436-10446
Author(s)

5-aminothiazoles reveal a new ligand-binding site on prolyl oligopeptidase which is important for modulation of its protein-protein interaction-derived functions

Source
Journal of medicinal chemistry - ISSN 0022-2623-67:7 (2024) p. 5421-5436
Author(s)
    Henri T. Patsi, Tommi P. Kilpelainen, Mikael Jumppanen, Johanna Uhari-Vaananen, Pieter Van Wielendaele, Francesca De Lorenzo, Hengjing Cui, Samuli Auno, Janne Saharinen, Erin Seppala, Nina Sipari, Juha Savinainen, Ingrid De Meester, Anne-Marie Lambeir, Maija Lahtela-Kakkonen, Timo T. Myohanen, Erik A.A. Wallen

Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases

Source
Frontiers in Chemistry - ISSN 2296-2646-10 (2023) p. 1-17
Author(s)