Evaluating the proarrhythmic risk of delayed-action compounds in serum free cell culture conditions; serum-starvation accelerates/amplifies the effect of probucol on the KCNQ1+KCNE1 channel

Source
Journal of pharmacological and toxicological methods - ISSN 1056-8719-130 (2024) p. 1-8
Author(s)
    Kenny Van Theemsche, Lisse Frans, Dieter Van de Sande, Evelyn Martínez Morales, Dirk Snyders, Alain J. Labro

Acute and delayed drug effects on voltage-gated potassium channels

Source
Antwerp, University of Antwerp & Ghent University, 2024,128 p.
Author(s)

The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels

Source
Science Advances - ISSN 2375-2548-8:37 (2022) p. 1-11
Author(s)
    Laura Coonen, Evelyn Martínez Morales, Dieter Van de Sande, Dirk Snyders, D. Marien Cortes, Luis G. Cuello, Alain Labro