Statistical opto-biomechanical eye model. 01/09/2024 - 31/08/2025

Abstract

Ophthalmic research has made significant progress, evolving from basic ocular refractive models to the sophisticated SyntEyes model. The latter model provides synthetic biometric datasets that reflect real eye statistics for improved optical calculations without additional measurements. However, to date its focus remained limited to optical characteristics, leaving out ocular biomechanics. To address this gap, the SyntEyes OBM (Synthetic Opto-Biomechanical Eye Model) is proposed as a comprehensive platform that integrates both optical and biomechanical properties of the eye to perform detailed analyses under different conditions. This advancement involved the development of a 3D geometric eye model including the cornea, limbus, sclera, lens, iris, ciliary body, and zonular fibres. The model uses Zernike coefficients to define the anterior and posterior surfaces of the cornea, extending their diameters to allow for realistic dimensions. The lens shape was derived from SyntEyes data using aspheric surfaces for accuracy. The sclera was modelled as a spherical shell of constant thickness connecting the corneal limbus to the retinal fovea, while the ciliary body and zonular fibres were customised based on previous research to ensure individual representation. The SyntEyes OBM model offers adaptability to multiple biometric variations, enhancing the original SyntEyes by incorporating biomechanical insights and allowing simultaneous and accurate evaluation of the optical and biomechanical aspects of the eye. This model will significantly enhance optical and clinical simulations, providing a more thorough and accurate tool for ophthalmic research and practice, and marking a notable advancement in the field.

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  • Research Project