The industrial biotechnology research at BioWAVE_IB is directed to using the biorefinery approach (microorganisms, enzymes and, sometimes, chemicals) for the valorisation of industrial side-streams for the production of commodity as well as high-value chemicals, such as bioethanol, long chain dicarboxylic acids, very-long-chain fatty acids and microbial oil. Eco-efficient processes are designed and optimized based on novel and improved pre-treatment technologies of the raw material, as well as the process conditions using biochemical engineering and modelling techniques. Different fermentation strategies, such as solid state fermentation, high solids fermentations, simultaneous saccharification and fermentation as well as submerged fermentations are applied.