Abstract
Modern organic synthesis provides a toolbox of methodologies which (at least theoretically) allows to make every single organic molecule. However, the efficiency (overall yield, number of steps, resources and time required) obtained in its multistep synthesis is often (very) low. Considering the strive for more sustainable organic synthesis and the need to access novel molecular libraries targeting specific applications (e.g. drug development), 'efficiency improvement' is a very important though very challenging goal. Direct(ed) transition metal-catalyzed strong bond functionalization (i.e. C-H and C-N) is an important contemporary research field obviating the need to preinstall leaving groups in organic molecules (indirect synthesis), which is still the standard procedure in organic synthesis. In this project a new convertible and recyclable directing group based on a diazole unit for C-H and C-N bond functionalization will be explored.
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