Potassium current inactivation as a novel pathomechanism for KCNQ2 developmental and epileptic encephalopathy
Source
Epilepsia - ISSN 0013-9580-66:6 (2025) p. e98-e105
In silico assisted identification, synthesis, and In vitro pharmacological characterization of potent and selective blockers of the epilepsy-associated KCNT1 channel
Source
Journal of medicinal chemistry - ISSN 0022-2623-67:11 (2024) p. 9124-9149
Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage
Source
American journal of physiology : cell physiology - ISSN 0363-6143-326:3 (2024) p. C893-C904
Beyond retigabine : design, synthesis, and pharmacological characterization of a potent and chemically stable neuronal Kv7 channel activator with anticonvulsant activity
Source
Journal of medicinal chemistry - ISSN 0022-2623-65:16 (2022) p. 11340-11364
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy
Source
Proceedings of the National Academy of Sciences of the United States of America - ISSN 0027-8424-119:15 (2022) p. 1-10