Lieselot Croes unpaid staff

Research Lieselot Croes

Research team

Investigation of DFNA5 as potential biomarker and tumour suppressor gene in 4 solid tumour types. 01/10/2016 - 30/09/2019

Abstract

This research project focuses on DFNA5 based upon strong indications for its role as tumour suppressor gene, its function in apoptosis and its potential role as early biomarker in cancer. DFNA5 was identified in 1998 in our lab, as a gene causing autosomal dominant non syndromic hearing loss [3]. Since then, a number of papers on DFNA5 have been published pointing towards a possible involvement in cancer [4-15].

Researcher(s)

Research team(s)

Project type(s)

  • Research Project

Investigation of DFNA5 as potential biomarker and tumour suppressor gene in 4 solid tumour types. 01/10/2014 - 30/09/2016

Abstract

This research project focuses on DFNA5 based upon strong indications for its role as tumour suppressor gene, its function in apoptosis and its potential role as early biomarker in cancer. DFNA5 was identified in 1998 in our lab, as a gene causing autosomal dominant non syndromic hearing loss [3]. Since then, a number of papers on DFNA5 have been published pointing towards a possible involvement in cancer [4-15].

Researcher(s)

Research team(s)

    Project type(s)

    • Research Project

    The role of the DFNA5 tumour suppressor gene in the tumourigenesis of solid tumours. 13/11/2013 - 31/10/2015

    Abstract

    The general aim of this study is to investigate the role of DFNA5 in tumourigenesis, both on the molecular and the preclinical level. Although the preliminary indications for an important role are strong, very few studies have investigated this8,9,10,14. Further investigations are highly recommended. One of the main aims is the development of DFNA5 as a molecular biomarker for cancer.

    Researcher(s)

    Research team(s)

      Project type(s)

      • Research Project