Abstract
Isocyanates are an important class of molecules due to their versatile reactivity, including nucleophilic addition reactions with alcohols and amines to produce carbamates and ureas, cycloaddition reactions with a variety of unsaturated compounds to generate heterocycles, and polymerization reactions with diols to produce polyurethanes. Isocyanates are therefore widely used as intermediates in pharmaceutical, agrochemical and polymer industries. Many methods for isocyanate synthesis starting from a variety of substrates are known, but they often require toxic or otherwise dangerous reagents or harsh reaction conditions limiting scope. The objective of this proposal is to develop new approaches from alkenes.
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