Research team
Expertise
Clinical biology (clinical pathology - laboratory medicine), with focus on diagnostics in hemato-oncology
Pharmacodynamic in vitro study of the effects of growth factors and inhibitors on human adult bone marrow-, cord blood- and fetal liver derived hematopoietic stem cells.
Abstract
There are two main objectives in this study: first, the effects of different growth factors and inhibitors on subpopulations of human hematopoietic stem cells, derived from ontogenetic different sources, will be investigated. Next, we will examine whether these subpopulations can be used as targets for gene therapy and whether they can be transduced using adeno-associated virus. The following techniques will be used: flow-cytometry, in vitro cell culture, gene transduction, DNA- and RNA-PCR.Researcher(s)
- Promoter: Berneman Zwi
- Fellow: Weekx Steven
Research team(s)
Project type(s)
- Research Project
Pharmacodynamic in vitro study of the effects of growth factors and inhibitors on human adult bone marrow-, cord blood- and fetal liver derived hematopoietic stem cells.
Abstract
There are two main objectives in this study: first, the effects of different growth factors and inhibitors on subpopulations of human hematopoietic stem cells, derived from ontogenetic different sources, will be investigated. Next, we will examine whether these subpopulations can be used as targets for gene therapy and whether they can be transduced using adeno-associated virus. The following techniques will be used: flow-cytometry, in vitro cell culture, gene transduction, DNA- and RNA-PCR.Researcher(s)
- Promoter: Berneman Zwi
- Fellow: Weekx Steven
Research team(s)
Project type(s)
- Research Project