The Global Hispanophone is intimately linked to the city of Antwerp and the region of Flanders: the origins of the Global Hispanophone literary and cultural production lie in the Spanish empire, of which Flanders was a part of. We certainly intend to problematize in our classes both Empire as a concept and its colonial repercussions by teaching from a decolonial perspective. Culture in Spanish was produced in Flanders and spread all over the world, from places like the Plantin Moretus printing house to the Meyer van Loo printing house, which in the 19th century published the subversive novel El filibusterismo, by the prominent Filipino author José Rizal. On the other hand, the port of Antwerp, from which thousands of Europeans left for the Americas and from which, in turn, thousands of Americans entered Europe, becomes relevant for debating questions of exile and diaspora.