Highlights in gastro-intestinal cancer

Bron
Belgian journal of medical oncology - ISSN 1784-7141-12 (2018) p. 182-188
Auteur(s)

AMG 193, a clinical stage MTA-cooperative PRMT5 inhibitor, drives antitumor activity preclinically and in patients with MTAP-deleted cancers

Bron
Cancer discovery - ISSN 2159-8274-15:1 (2025) p. 139-161
Auteur(s)
    Brian Belmontes, Katherine K. Slemmons, Chun Su, Siyuan Liu, Antonia N. Policheni, Jodi Moriguchi, Hong Tan, Fang Xie, Daniel Andrew Aiello, Yajing Yang, Raul Lazaro, Famke Aeffner, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Mikkel Vestergaard, Sanne Cowland, Jan Andersson, Ian Sarvary, Qing Chen, Pooja Sharma, Patricia Lopez, Nuria Tamayo, Liping H. Pettus, Sudipa Ghimire-Rijal, Susmith Mukund, Jennifer R. Allen, Jason Devoss, Angela Coxon, Jordi Rodon, Francois Ghiringhelli, Nicolas Penel, Hans Prenen, Sanne Glad, Chen-Hua Chuang, Kiana Keyvanjah, Danielle M. Townsley, John R. Butler, Matthew P. Bourbeau, Sean Caenepeel, Paul E. Hughes

Challenges and prospects of LAG-3 inhibition in advanced gastric and gastroesophageal junction cancer : insights from the RELATIVITY-060 trial

Bron
Journal of Gastrointestinal Oncology - ISSN 2078-6891-15:6 (2024) p. 2735-2738

Phase Ib study of the immunocytokine simlukafusp alfa (FAP-IL2v) in combination with cetuximab in patients with head and neck squamous cell carcinoma

Bron
Clinical cancer research - ISSN 1078-0432-30:24 (2024) p. 5540-5547
Auteur(s)
    Aaron R. Hansen, Carlos A. Gomez-Roca, Debbie G.J. Robbrecht, Loic Verlingue, Antoine Italiano, Julie E. Bauman, Neeltje Steeghs, Hans Prenen, Jerome Fayette, James Spicer, Jiaxin Niu, Christin Habigt, Meike Schneider, Stefan Evers, Nassim Sleiman, David Dejardin, Caroline Ardeshir, Daniela Schmid, Christophe Boetsch, Jehad Charo, Anton Kraxner, Volker Teichgraeber, Nino Keshelava, Marcelo R. Bonomi

First-in-human study of AMG 193, an MTA-cooperative PRMT5 inhibitor, in patients with MTAP-deleted solid tumors : results from phase I dose exploration

Bron
Annals of oncology - ISSN 0923-7534-35:12 (2024) p. 1138-1147
Auteur(s)
    J. Rodon, Hans Prenen, A. Sacher, M. Villalona-Calero, N. Penel, A. El Helali, S. Rottey, N. Yamamoto, F. Ghiringhelli, M.E. Goebeler, T. Doi, S. Postel-Vinay, C.-C. Lin, C. Liu, C.-H. Chuang, K. Keyvanjah, T. Eggert, B.H. O'Neil