Lidia Carotenuto postdoctoraal bursaal

Publicaties Lidia Carotenuto

Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage

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American journal of physiology : cell physiology - ISSN 0363-6143-326:3 (2024) p. C893-C904
Auteur(s)
    Camilla Celentano, Lidia Carotenuto, Francesco Miceli, Giusy Carleo, Brunella Corrado, Giulia Baroli, Stefania Iervolino, Raffaele Vecchione, Maurizio Taglialatela, Vincenzo Barrese

In silico assisted identification, synthesis, and In vitro pharmacological characterization of potent and selective blockers of the epilepsy-associated KCNT1 channel

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Journal of medicinal chemistry - ISSN 0022-2623-67:11 (2024) p. 9124-9149
Auteur(s)
    Nunzio Iraci, Lidia Carotenuto, Tania Ciaglia, Giorgio Belperio, Francesca Di Matteo, Ilaria Mosca, Giusy Carleo, Manuela Giovanna Basilicata, Paolo Ambrosino, Rita Turcio, Deborah Puzo, Giacomo Pepe, Isabel Gomez-Monterrey, Maria Virginia Soldovieri, Veronica Di Sarno, Pietro Campiglia, Francesco Miceli, Alessia Bertamino, Carmine Ostacolo, Maurizio Taglialatela

Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy

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Proceedings of the National Academy of Sciences of the United States of America - ISSN 0027-8424-119:15 (2022) p. 1-10
Auteur(s)
    Mario Nappi, Vincenzo Barrese, Lidia Carotenuto, Gaetan Lesca, Audrey Labalme, Dorothee Ville, Thomas Smol, Mélanie Rama, Anne Dieux-Coeslier, Clotilde Rivier-Ringenbach, Maria Virginia Soldovieri, Paolo Ambrosino, Ilaria Mosca, Michael Pusch, Francesco Miceli, Maurizio Taglialatela

Beyond retigabine : design, synthesis, and pharmacological characterization of a potent and chemically stable neuronal Kv7 channel activator with anticonvulsant activity

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Journal of medicinal chemistry - ISSN 0022-2623-65:16 (2022) p. 11340-11364
Auteur(s)
    Simona Musella, Lidia Carotenuto, Nunzio Iraci, Giulia Baroli, Tania Ciaglia, Piera Nappi, Manuela Giovanna Basilicata, Emanuela Salviati, Vincenzo Barrese, Vincenzo Vestuto, Giuseppe Pignataro, Giacomo Pepe, Eduardo Sommella, Veronica Di Sarno, Michele Manfra, Pietro Campiglia, Isabel Gomez-Monterrey, Alessia Bertamino, Maurizio Taglialatela, Carmine Ostacolo, Francesco Miceli

KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism

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EBioMedicine - ISSN 2352-3964-81 (2022) p. 1-15
Auteur(s)
    Francesco Miceli, Charissa Millevert, Maria Virginia Soldovieri, Ilaria Mosca, Paolo Ambrosino, Lidia Carotenuto, Dewi Schrader, Hyun Kyung Lee, James Riviello, William Hong, Sarah Risen, Lisa Emrick, Hitha Amin, Dorothée Ville, Patrick Edery, Julitta de Bellescize, Vincent Michaud, Julien Van-Gils, Cyril Goizet, Marjolein H. Willemsen, Tjitske Kleefstra, Rikke S. Møller, Allan Bayat, Orrin Devinsky, Tristan Sands, G. Christoph Korenke, Gerhard Kluger, Heather C. Mefford, Eva Brilstra, Gaetan Lesca, Mathieu Milh, Edward C. Cooper, Maurizio Taglialatela, Sarah Weckhuysen