Lorenzo Cianni postdoctoraal bursaal

Publicaties Lorenzo Cianni

Design, synthesis and stepwise optimization of nitrile-based inhibitors of cathepsins B and L

Bron
Bioorganic and medicinal chemistry - ISSN 0968-0896-29 (2021) p.
Auteur(s)
    Lorenzo Cianni, Fernanda Reis Dos Rocho, Vinicius Bonatto, Felipe Cardoso Prado Martins, Jeronimo Lameira, Andrei Leitao, Carlos A. Montanari, Anwar Shamim

Crystal structure of Leishmania mexicana cysteine protease B in complex with a high-affinity azadipeptide nitrile inhibitor

Bron
Bioorganic and medicinal chemistry - ISSN 0968-0896-28:22 (2020) p.
Auteur(s)
    Jean F.R. Ribeiro, Lorenzo Cianni, Chan Li, Thomas G. Warwick, Daniela de Vita, Fabiana Rosini, Fernanda Reis dos Rocho, Felipe C.P. Martins, Peter W. Kenny, Jeronimo Lameira, Andrei Leitao, Jonas Emsley, Carlos A. Montanari

Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases

Bron
Bioorganic chemistry - ISSN 0045-2068-101 (2020) p.
Auteur(s)
    Lorenzo Cianni, Fernanda Reis dos Rocho, Fabiana Rosini, Vinicius Bonatto, Jean F.R. Ribeiro, Jeronimo Lameira, Andrei Leitao, Anwar Shamim, Carlos A. Montanari

Mapping the S1 and S1' subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents

Bron
PLoS neglected tropical diseases - ISSN 1935-2735-14:3 (2020) p.
Auteur(s)
    Lorenzo Cianni, Carina Lemke, Erik Gilberg, Christian Feldmann, Fabiana Rosini, Fernanda Reis dos Rocho, Jean F.R. Ribeiro, Daiane Y. Tezuka, Carla D. Lopes, Sergio de Albuquerque, Juergen Bajorath, Stefan Laufer, Andrei Leitao, Michael Guetschow, Carlos A. Montanari