Chemoselective synthesis and anti-kinetoplastidal properties of 2,6-diaryl-4H-tetrahydro-thiopyran-4-one S-oxides : their interplay in a cascade of redox reactions from diarylideneacetones
Source
Molecules: a journal of synthetic chemistry and natural product chemistry - ISSN 1420-3049-29:7 (2024) p. 1-25
Long-term hematopoietic stem cells trigger quiescence in Leishmania parasites
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PLoS pathogens - ISSN 1553-7374-20:4 (2024) p. 1-21
Lead optimization of the 5-phenylpyrazolopyrimidinone NPD-2975 toward compounds with improved antitrypanosomal efficacy
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Journal of medicinal chemistry - ISSN 0022-2623-67:4 (2024) p. 2849-2863
DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc₁
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Science translational medicine - ISSN 1946-6234-15:726 (2023) p.
Discovery of 5-phenylpyrazolopyrimidinone analogs as potent antitrypanosomal agents with in vivo efficacy
Source
Journal of medicinal chemistry - ISSN 0022-2623-66:15 (2023) p. 10252-10264